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Description

Disruptions in energy metabolism not only drive the abnormal proliferation of cancer cells and synovial fibroblasts but also lead to imbalances in the differentiation of immune cell populations, including Th17 cells, Tfh cells, Treg cells, and macrophages

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Collectively, these findings indicate that DM-associated metabolic dysregulation can directly induce pulmonary vascular injury by disrupting autophagy